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Thermo Orbitrap Elite coupled with Thermo EASY-nLC 1000
High resolution, speed and sensitivity make this instrument a perfect choice for the analysis of samples with low amount of protein (like silver-stained) gels and mapping of posttranslational modifications.
Thermo Q Exactive coupled with Waters nanoAcquity UPLC
Hybrid mass spectrometer with quadrupole-type mass analyzer and Orbitrap detector. Due to the high resolution and speed it is used mainly in qualitative and quantitative proteomic profiling of very complex protein mixtures.
Thermo Orbitrap Velos coupled with Waters nanoAcquity UPLC
One of the best setups on the market for proteomic analysis. Only 10 pgram (140 attomol) of digested BSA is enough for reliable identification and about 20% protein sequence coverage. As for complex mixtures using 3-hour gradient it can get over 500 identified proteins. Mass Spectrometry Laboratory has three such systems from which one is equipped with a module that allows to perform ETD fragmentation.
Waters SYNAPT HDMS coupled with Waters nanoAcquity UPLC
Waters SYNAPT HDMS hybrid Q-TOF pectrometer is the only one on the market equipped with Ion Mobility module, allowing the separation of isobaric fragments of the analyzed substances. Additionally our setup allows perform ETD fragmentation.
Bruker ultrafleXtreme MALDI-TOF/TOF
MALDI is an alternative to electrospray ionization type. This spectrometer offers a very fast and modern laser and advanced ion optics system, which allows to obtain high sensitivity and mass accuracy of peptides analysis. It is used primarily for rapid identification of proteins from gels and to measure the masses of whole proteins.
Waters Q-TOF Premier coupled with nanoAcquity UPLC Waters
Older generation hybrid spectrometer - despite many years of work in our lab it is still used in routine analysis.
Waters SYNAPT MS coupled with Waters nanoAcquity UPLC with TRIZAIC technology or Waters Acquity UPLC
The latest generation hybrid spectrometer equipped with nano and standard UPLC. Used mainly in metabolomic and structural research.
Waters Xevo TQ-S coupled with Waters Acquity UPLC
The latest generation triple quadrupole mass spectrometer Waters Xevo TQ-S featuring novel StepWave ion optics. It is dedicated to the quantification of small molecules and peptides. It equipped with ESI, APCI, APPI, and optionally nanoESI. Our laboratory has two such setsups.
WatersXevo TQ-MS coupled with Waters Acquity UPLC or Waters nanoAcquity UPLC
A triple quadrupole mass spectrometer dedicated to routine quantification. It has the ability to work with ESI, APCI, and optionally nanoESI and APPI. Our lab has two such sets.